Monday, October 30, 2023

" Types of GLP-1 agonists "




There are several GLP-1 agonist medications available, and they differ in terms of dosing frequency, administration method, and other features. some common GLP-1 agonist medications include:


  • Exenatide (Byetta, Bydureon)

  • Liraglutide (Victoza, Saxenda)

  • Dulaglutide (Trulicity)

  • Semaglutide (Ozempic)

  • Lixisenatide (Adlyxin)

  • Albiglutide (Tanzeum) - Note that Tanzeum was withdrawn from the market in 2017.

  • Lixisenatide/Insulin Glargine (Soliqua 100/33)

  • Semaglutide/Rybelsus (Rybelsus) - A tablet formulation


New medications may have been approved and introduced to the market since this post I recommend consulting with a healthcare provider or checking with a reliable medical source for the most up-to-date information on GLP-1 agonist medications. It's important to discuss with a healthcare professional to determine which specific medication is most suitable for your condition and needs.


" Types of insulin "







There are several different types of insulin, each with specific characteristics that determine how quickly they start working, when they peak in activity, and how long their effects last. Insulin can be categorized into several types:

Rapid-Acting Insulin:

  • Insulin Lispro (Humalog)
  • Insulin Aspart (NovoLog)
  • Insulin Glulisine (Apidra)

Short-Acting Insulin:

  • Regular Insulin (Humulin R, Novolin R)
  • Intermediate-Acting Insulin:
  • NPH Insulin (Humulin N, Novolin N)

Long-Acting Insulin:

  • Insulin Glargine (Lantus, Basaglar, Toujeo)
  • Insulin Detemir (Levemir)
  • Insulin Degludec (Tresiba)

Ultra-Long-Acting Insulin:

Insulin Degludec (Tresiba) is considered an ultra-long-acting insulin due to its extended duration of action.

Pre-Mixed Insulin:

Various formulations contain a combination of short-acting and intermediate-acting insulins. Examples include Humulin 70/30 and Novolog 70/30.

Inhaled Insulin:

Afrezza (inhaled insulin powder) is a rapid-acting insulin used before meals.

It's important to note that the specific names and availability of insulin products may vary by region and may change over time due to new formulations and generic versions becoming available. The choice of insulin type and regimen is determined by an individual's diabetes management plan and the advice of a healthcare provider. Insulin is prescribed and dosed based on an individual's specific needs, which can vary widely depending on factors such as the type of diabetes, lifestyle, and blood sugar control goals.










" What are the dangers of using GLP1 for solely weight loss? "




Using GLP-1 medications strictly for weight loss without a medical indication or supervision can be associated with several potential dangers and concerns:

Safety Risks: GLP-1 medications are designed for the management of type 2 diabetes. They can have side effects, and not everyone can safely use these drugs. Using them without proper medical oversight can lead to unexpected side effects or complications.

Nausea and Gastrointestinal Issues: One of the common side effects of GLP-1 medications is nausea and gastrointestinal discomfort. Taking these medications solely for weight loss may subject individuals to these side effects unnecessarily.

Dehydration: Some people may experience diarrhea as a side effect of GLP-1 medications, which can lead to dehydration, especially if they are not adequately compensating for the fluid loss.

Blood Sugar Regulation: GLP-1 medications are designed to lower blood sugar levels. In individuals without diabetes, these medications can lead to hypoglycemia (low blood sugar), which can be dangerous.

Inadequate Weight Loss: Not everyone will experience significant weight loss with GLP-1 medications. Relying solely on these drugs for weight loss without making appropriate lifestyle changes may lead to disappointment.

Tolerance and Reduced Efficacy: Over time, the body may become less responsive to GLP-1 medications, reducing their effectiveness for weight loss. This is why they are typically prescribed for diabetes management rather than as long-term weight loss agents.

Financial Costs: GLP-1 medications can be expensive, and using them for off-label purposes can result in unnecessary healthcare expenses.

Limited Long-Term Data: The long-term effects of using GLP-1 medications for weight loss in individuals without diabetes are not well-studied. It's unclear what potential risks or consequences might arise with prolonged use for this purpose.

Misuse and Abuse: Using prescription medications for non-medical purposes, such as weight loss, can lead to misuse and even abuse. This can be harmful to an individual's overall health and well-being.

Lack of Lifestyle Changes: Relying solely on medication for weight loss can undermine the importance of making sustainable lifestyle changes, including dietary modifications and regular physical activity. These changes are crucial for long-term weight management and overall health.

If you are interested in using GLP-1 medications for weight loss, it's essential to consult with a healthcare provider. They can assess your individual health, weight management goals, and the potential risks and benefits of using these medications. In many cases, healthcare providers may recommend alternative weight loss strategies, including dietary changes, exercise, and behavioral therapy, before considering medications, especially if you don't have a medical need for GLP-1 agonists. Always prioritize a comprehensive and medically supervised approach to weight management to ensure your safety and well-being.

Monday, October 16, 2023

" Insulin vs. GLP-1 Medications: A Comprehensive Comparison "

"Disclaimer: I am not a medical advisor or healthcare professional. The information shared in this blog is based on my personal experiences and research. Please consult a qualified healthcare provider or medical professional for personalized advice and recommendations for your health and medical treatments."

Living with diabetes often requires medications to manage blood sugar levels. While insulin and GLP-1 medications are essential tools in diabetes management, they function differently and have distinct pros and cons. Type 1 diabetes is characterized by the body's inability to produce insulin on its own. Treatment aims to replace the insulin your pancreas cannot produce. However, Type 2 diabetes means that your body no longer uses insulin effectively. Keeping your blood sugar levels in an optimal range is difficult when your body cannot produce enough insulin.Today's post explores the key differences and similarities between insulin and GLP-1 medications to help you better understand these two essential treatment options. 

1. Mechanism of Action: 

Insulin: Insulin is a hormone naturally produced by the pancreas, and insulin medications work by replacing or supplementing the body's insulin. It helps glucose enter cells for energy. 

GLP-1 Medications: GLP-1 medications, on the other hand, mimic the action of a hormone called GLP-1. They stimulate insulin release, suppress glucagon, and slow digestion to lower blood sugar levels. 

2. Administration: 

Insulin: Insulin is typically administered via injections, either through a syringe, insulin pen, or insulin pump. 

GLP-1 Medications: GLP-1 medications are also injected but come in pre-filled pens or syringes. Some GLP-1 medications can be taken orally. 

3. Timing and Flexibility: 

Insulin: Insulin must often be taken at specific times, and dosages may need to be adjusted frequently based on blood sugar levels, meals, and physical activity. 

GLP-1 Medications: GLP-1 medications are typically taken once daily or weekly, offering more dosing flexibility. 

4. Weight Impact: 

Insulin: Insulin can lead to weight gain in some individuals, especially when blood sugar levels are uncontrolled. 

GLP-1 Medications: GLP-1 medications are often associated with weight loss or neutrality, making them appealing to those concerned about weight management. 

5. Hypoglycemia Risk: 

Insulin: Insulin carries a higher risk of hypoglycemia (low blood sugar) if not dosed and timed correctly. 

GLP-1 Medications: GLP-1 medications have a lower risk of hypoglycemia, primarily when used as monotherapy. 

6. Targeted Use: 

Insulin: Insulin is commonly used for people with type 1 diabetes and some individuals with type 2 diabetes. 

GLP-1 Medications: GLP-1 medications are more widely prescribed for people with type 2 diabetes. 

7. Side Effects: 

Insulin: Side effects may include weight gain, hypoglycemia, and injection site reactions. 

GLP-1 Medications: Side effects can cause nausea, vomiting, and diarrhea in some individuals. 

In managing diabetes, the choice between insulin and GLP-1 medications depends on individual needs, lifestyle, and the specific requirements of each case. It's essential to work closely with your healthcare provider to determine which medication is the most suitable for your diabetes management plan. This comparison should serve as a starting point for understanding the critical differences between these two essential types of diabetes medications. 

" Diabetes & Me: My Back Story "




My journey began in the shadows of obesity. A journey marked not only by excess weight but also by the determination to free myself from its burdensome chains. At my heaviest weight, I tipped the scales at over 400 pounds, and that's when I realized I had to embark on a journey toward change. 
This is the story of my journey to fitness—a monumental quest to shed weight and reclaim my health—and the role that a glp-1 medication played in this odyssey.

I struggled with obesity in my adolescent years and even as an adult. I can remember In the 5th grade, I weighed about 200 pounds. Food served as a refuge for me during my youth when I experienced abuse from molestation and other things. In addition, food was an expression of love and a gift from my beloved aunt, which provided me with comfort. I experienced a dramatic change in my life as I grew up. Following my aunt's death, I moved into my dad's house. Unaware of the severity of my weight, I became very defensive and rebellious when he brought up my weight.

In those days, I felt comfortable in my own skin. After gaining so much weight, I didn't realize how dangerous it had become for me. Three years ago, I changed my diet after staying the same for a long time. During that period, I noticed a change in my body, and my menstrual cycle was out of sync. I used to go on for days, even months, without a menstrual cycle. I remember going through a menstrual cycle for a year and was told by the ER that I probably wouldn't have been here if I hadn't arrived when I did. 

I began to realize that my weight had now become a problem. And I was told I had PCOS, and I was notified. Polycystic ovary syndrome (PCOS) is a common reproductive disorder that affects people with ovaries, most often during their reproductive years. It is characterized by irregular menstrual cycles, elevated androgen (male hormones) levels in the body, and the formation of small fluid-filled sacs (cysts) on the ovaries. PCOS can cause weight gain, acne, hirsutism (excessive hair growth), and fertility problems. To lower my blood sugar and lose weight, I was given a tablet-type of medication in light of this new information.

As we approach 2022, (a1c, also referred to as hemoglobin a1c or hba1c) is a blood test that measures your normal blood sugar levels. As part of diabetes prevention, the test provides valuable information about how well a person's blood sugar levels have been monitored over time.) Although my levels had improved, it wasnt in the range my doctor wanted it to be, so I was prescribed other drugs that didn't work for me. I declined my doctor's subsequent recommendation of injectable insulin due to my personal research. Fast forward to the late winter of 2023.

 As I was strolling through TikTok, I noticed a lot of people talking about glp-1 drugs. I began to be intrigued about people testimonies. As a result, I decided to do some research on the risks, concerns, and benefits that may be associated with glp-1 drugs, so I decided to take action and discuss it with my doctor in order to get some additional advice before taking any further steps. My doctor accepted, and we began my first month of the medication. As a result of these actions, I lost 66 pounds over the course of 34 weeks and 4 days, and my a1c decreased from 7.2 to 6.5. My progress has been amazing, and I'm so proud of it. This journey isn't over. So join me as I share my research , knowledge, trials, triumphs, and the incredible power of resilience and medical intervention on the journey to a healthier me.

" What are Dual GLP-1/GIP receptor agonists ? "

Dual GLP-1/GIP receptor agonists are a class of medications used to treat type 2 diabetes and obesity. GLP-1 (glucagon-like peptide-1) and G...